EDUCATIONAL CONTENT ONLY - We do not sell, supply, or distribute Zepbound
Educational Resource

Understanding Zepbound® in Nigeria

Comprehensive information about Zepbound (tirzepatide), its regulatory status in Nigeria, and what alternatives are available for weight management.

Not NAFDAC Registered

Cannot be legally sold

Active: Tirzepatide

Dual GIP/GLP-1 agonist

Alternatives Available

Compounded tirzepatide

Understanding the Medication

What Is Zepbound®?

Zepbound is the brand name for tirzepatide, a prescription medication manufactured by Eli Lilly and Company. It was approved by the U.S. Food and Drug Administration (FDA) in November 2023 specifically for chronic weight management in adults with obesity (BMI of 30 or greater) or overweight (BMI of 27 or greater) with at least one weight-related condition.

Zepbound is the same active ingredient as Mounjaro, which is approved for type 2 diabetes management. While Mounjaro targets diabetes, Zepbound is specifically approved and marketed for weight loss.

How Tirzepatide Works

1

GLP-1 Receptor Activation

Mimics the GLP-1 hormone, which signals fullness to your brain, slows stomach emptying, and helps regulate blood sugar levels after meals.

2

GIP Receptor Activation

Also targets the GIP hormone receptor, which enhances insulin secretion and may improve fat metabolism. This dual-action is unique to tirzepatide.

Clinical Trial Results (SURMOUNT-1)

In the 72-week SURMOUNT-1 clinical trial, participants on the highest dose of tirzepatide (15mg) achieved:

  • 22.5% average body weight reduction
  • 63% of participants lost 20% or more of body weight
  • Significant improvements in cardiovascular risk factors

Source: SURMOUNT-1 trial published in the New England Journal of Medicine, 2022.

Important Information

Regulatory Status in Nigeria

Zepbound Is NOT Registered with NAFDAC

As of January 2026, Zepbound (tirzepatide for weight loss) has not been registered with the National Agency for Food and Drug Administration and Control (NAFDAC) in Nigeria. This means it cannot be legally imported, sold, or distributed in Nigeria.

Cannot Purchase Legally

Any entity claiming to sell genuine Zepbound in Nigeria is operating outside the law. NAFDAC has not approved this medication for sale.

No Import Authorization

Importing Zepbound for personal use or commercial sale without NAFDAC approval violates Nigerian pharmaceutical regulations.

Counterfeit Risk

Products sold as "Zepbound" in Nigeria may be counterfeit, expired, or improperly stored, posing serious health risks.

NAFDAC Verification

You can verify any medication's registration status at nafdac.gov.ng or by calling NAFDAC directly.

About NAFDAC

The National Agency for Food and Drug Administration and Control (NAFDAC) is Nigeria's regulatory body responsible for ensuring that all food, drugs, cosmetics, medical devices, and chemicals are safe for consumption and use. Any prescription medication must be registered with NAFDAC before it can be legally sold in Nigeria.

The Science

The Active Ingredient: Tirzepatide

Tirzepatide is the active pharmaceutical ingredient in both Zepbound (for weight loss) and Mounjaro (for type 2 diabetes). It represents a new class of medications called dual GIP/GLP-1 receptor agonists.

While the branded versions are not available in Nigeria, compounded tirzepatide - containing the same active ingredient prepared by licensed compounding pharmacies - may be available through authorized providers.

Compounded medications are custom-prepared by pharmacists and can provide access to medications when brand-name versions are unavailable or unaffordable.

Tirzepatide Facts

  • Weekly subcutaneous injection
  • First-in-class dual GIP/GLP-1 agonist
  • Developed by Eli Lilly and Company
  • Available in 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg doses
  • Requires refrigeration (2-8°C)
Available Options

Alternatives in Nigeria

While Zepbound is not available, Nigerians seeking GLP-1 weight loss therapy have options through providers offering compounded tirzepatide and semaglutide.

Important Note

These providers offer compounded tirzepatide (the same active ingredient as Zepbound), not the brand-name product. Always consult with a healthcare provider before starting any weight loss medication. Verify any provider's legitimacy before making purchases.

Common Questions

Frequently Asked Questions

No. Zepbound (the brand-name product from Eli Lilly) is not registered with NAFDAC and cannot be legally purchased in Nigeria. Any entity claiming to sell genuine Zepbound in Nigeria is likely selling counterfeit products or operating illegally. However, compounded tirzepatide (the same active ingredient) may be available through legitimate providers.

The brand-name products (Zepbound and Mounjaro) are not NAFDAC-approved, so they cannot be legally sold. However, compounded medications prepared by licensed pharmacies operate in a different regulatory category. If you're considering tirzepatide therapy, consult with a healthcare provider who can guide you on legally available options.

Both contain the exact same active ingredient: tirzepatide. The only differences are:

  • Mounjaro is approved for type 2 diabetes management
  • Zepbound is approved specifically for chronic weight management
  • They may have different pricing and insurance coverage in countries where both are available

Neither is currently available through official channels in Nigeria.

Nigerians seeking GLP-1 weight loss therapy have several options:

  • Compounded tirzepatide - Same active ingredient, prepared by compounding pharmacies
  • Compounded semaglutide - Another GLP-1 medication (same ingredient as Ozempic/Wegovy)
  • Lifestyle programs - Diet and exercise programs supervised by healthcare providers

See the Alternatives section for providers offering these options.

Look for these indicators of a legitimate provider:

  • Requires medical consultation before prescribing
  • Has licensed healthcare providers on staff
  • Provides clear information about what they're selling (compounded vs. brand-name)
  • Uses proper cold-chain storage and delivery
  • Has verifiable contact information and physical presence
  • Does NOT claim to sell "genuine Zepbound" (since it's not available in Nigeria)

Common side effects of tirzepatide include:

  • Nausea (most common, usually improves over time)
  • Diarrhea or constipation
  • Decreased appetite
  • Vomiting
  • Abdominal pain
  • Injection site reactions

Serious side effects are rare but can include pancreatitis, gallbladder problems, and hypoglycemia (when used with other diabetes medications). Always use under medical supervision.